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doi: 10.1016/S0015-0282(01)02735-2

Farbers pioneering use of antifolate drugs established cancer chemotherapy, and another folate antagonist, methotrexate, remains a key component of childhood acute lymphoblastic leukemia (ALL) treatment, with a cure rate of up to 90% when combined with l-asparaginase

Personalized quantitative models of NAD metabolism in hepatocellular carcinoma identify a subgroup with poor prognosis

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